API Contract Manufacturing for Pharmaceutical Intermediates
Quality, Constancy, Reliability,
Confidentiality, Scalability, and Partnership
PYG Lifesciences is an ISO Certified company and operating as per cGMP, Contract Manufacturing Organization (CMO) based in India, specializing in contract manufacturing for pharmaceutical API intermediates, advanced
intermediates & speciality chemicals. We manufacture and supply products precisely to our customers’ specifications, backed by robust manufacturing infrastructure, skilled technical teams, and comprehensive quality management systems that ensure consistent quality, regulatory compliance, and reliable delivery.
From technology transfer to commercial manufacturing, PYG Lifesciences is your trusted pharmaceutical contract manufacturing partner, combining proven manufacturing capabilities, deep technical expertise, and robust quality management systems to deliver consistent quality and a reliable commercial supply.
MANUFACTURING INFRASTRUCTURE BUILT FOR PHARMACEUTICAL CHEMISTRY
LIST OF PLANT EQUIPMENT AND
MACHINERY
| SR. NO. | NAME OF EQUIPMENT/MACHINERY | CAPACITY | QTY | UOM |
| 01 | GLR REACTOR ASSEMBLY | 3 KL | 5 | NOS. |
| 02 | GLR REACTOR ASSEMBLY | 2 KL | 2 | NOS. |
| 03 | SSR REACTOR ASSEMBLY | 2 KL | 2 | NOS. |
| 04 | SSR REACTOR ASSEMBLY | 2 KL | 1 | NOS. |
| 05 | STEAM TRAY DRYER | 48 TRAY | 2 | NOS. |
| 06 | ROTATORY CONE VACUUM DRYER (RCVD) | 48 TRAY | 1 | NOS. |
| 07 | CENTRIFUGE | 36″ | 3 | NOS. |
| 08 | QUENCHER | 3 KL | 1 | NOS. |
| 09 | FBD | 200 Kg | 1 | NOS. |
| 10 | PULVERIZER | 100 Kg | 1 | NOS. |
| 11 | SPARKLER FILTER PRESS | 12 PLATES | 1 | NOS. |
| 12 | NEUTCHE FILTER | 100 LIT | 2 | NOS. |
MANUFACTURING & OPERATIONAL
CAPABILITIES
| SR. NO. | REACTION CAPABILITIES | REMARKS |
| 01 | Friedel-Crafts | Temp ranges (-)50°C to 200°C |
| 02 | Hofmann Reaction | Amide to primary amine conversion under controlled conditions |
| 03 | Halogenations | Chlorination & Bromination capabilities with containment controls |
| 04 | Sandmeyer | Diazotization & nucleophilic substitution for aryl halide synthesis |
| 05 | Suzuki Coupling | Palladium-catalyzed C-C bond formation for complex biaryls |
| 06 | Condensation | Acid/Base catalyzed C-C & C-N bond formation at commercial scale |
| 07 | Oxidation / Reduction | Acid/Base catalyzed C-C & C-N bond formation at commercial scale |
| 08 | Nitration | Acid/Base catalyzed C-C & C-N bond formation at commercial scale |
| 09 | Grignard Reaction | Acid/Base catalyzed C-C & C-N bond formation at commercial scale |
| SR. NO. | ANALYSING & QC INSTRUMENTS. |
| 01 | HPLC |
| 02 | GC |
| 03 | KF Titrator |
| 04 | Melting Point/Boiling Point Apparatus |
| 05 | Muffle Furnace |
| 06 | Sonicator |
| 07 | U.V. Cabinet |
| 08 | Analytical Weighing Balance |
| 09 | pH/Conductivity Meter |
FREQUENTLY ASKED QUESTIONS
What is contract manufacturing?
Contract manufacturing is a business model where a pharmaceutical company outsources manufacturing to a specialized partner. In API contract manufacturing, the manufacturer produces pharmaceutical intermediates or APIs according to the customer’s validated process and quality specifications.
What is the difference between a CMO and a CDMO?
A Contract Manufacturing Organization (CMO) manufactures products using a customer-provided process, while a CDMO develops the process and manufactures it. PYG Lifesciences operates as a Contract Manufacturing Organization (CMO) focused on manufacturing execution and commercial supply.
How does technology transfer work at PYG Lifesciences?
The process begins with documentation review, followed by technical evaluation, pilot validation, quality assessment, and commercial manufacturing approval to ensure a smooth transition into production.
Is PYG Lifesciences a cGMP-compliant manufacturer?
Yes. PYG Lifesciences operates a cGMP-certified manufacturing facility supported by documented quality systems, experienced technical teams, and commercial-scale infrastructure.
Does PYG Lifesciences have in-house QC capabilities?
Yes. PYG Lifesciences operates an in-house quality control laboratory equipped with HPLC, GC, KF Titrator, UV Cabinet, Analytical Weighing Balance, pH/Conductivity Meter, and other analytical instruments used for batch verification and quality assessment.
What reaction chemistries does PYG support?
PYG supports Friedel-Crafts, Hofmann Reaction, Halogenations, Sandmayer, Suzuki Coupling, Condensation, Oxidation/Reduction, Nitration, and Grignard Reaction across a temperature range of -50°C to 200°C.
Why choose PYG Lifesciences over other API contract manufacturing companies?
Among leading API contract manufacturing companies, PYG Lifesciences offers cGMP-certified infrastructure, experienced technical teams, robust quality systems, and reliable commercial-scale manufacturing for pharmaceutical API intermediates.
